Merck KGaA replaces Merck Serono SA In The S&P European Indices

Standard & Poor’s will make the following changes in the S&P Europe 350, S&P Euro Plus and S&P Euro indices effective after the close of trading on Friday 09 February 2007:

• Merck KGaA (Germany, SEDOL: 4741844, GICS: Health Care, GICS Code: 35202010) will replace Merck Serono SA (Switzerland, SEDOL: 4981070, GICS: Health Care, GICS Code: 35201010) in the S&P Europe 350 and S&P Euro Plus indices, and will be added to the S&P Euro index, following its acquisition of 97% of Merck Serono shares.

Merck KGaA is a leading pharmaceuticals and chemicals company. The number of shares outstanding will be 217,361,000 and the Investable Weight Factor will be 0.2972 reflecting the unquoted Merck family holding in the company. The company will be added to the S&P Europe 350 GICS (Global Industry Classification Standard) Pharmaceuticals sub-industry.

Following is a summary of the announced addition and deletion:

S&P Europe 350, S&P Euro Plus and S&P Euro – close of trading Friday 09 February 2007
	COMPANY	GICS ECONOMIC SECTOR	GICS SUB-INDUSTRY
ADDED	Merck KGaA	Health Care	Pharmaceuticals
DELETED	Merck Serono SA	Health Care	Biotechnology