Shire plc To Join The NASDAQ-100 Index Beginning October 19, 2016

Nasdaq (Nasdaq:NDAQ) today announced that Shire plc (Nasdaq:SHPG), will become a component of the NASDAQ-100 Index® (Nasdaq:NDX) and the NASDAQ-100 Equal Weighted Index (Nasdaq:NDXE) prior to market open on Wednesday, October 19, 2016. Shire plc will replace Linear Technology Corporation (Nasdaq:LLTC) in the indexes.

Shire plc is headquartered in Dublin, Republic of Ireland, and has a market capitalization of approximately $18 billion. For more information about the company, go to www.shire.com.