Mondo Visione Worldwide Financial Markets Intelligence

FTSE Mondo Visione Exchanges Index:

Component Deletion From The Nasdaq Biotechnology Index Effective On May 14, 2001

Date 11/05/2001

BioChem Pharma Inc. (Nasdaq:BCHE) will be deleted as a component of the Nasdaq Biotechnology Index® (Nasdaq:NBI), effective at the beginning of trading Monday, May 14, 2001. BioChem Pharma Inc. is being acquired by Shire Pharmaceuticals Group plc (Nasdaq:SHPGY). As a result, the Index will then include 75 companies.

The Nasdaq Biotechnology Index, launched on November 1, 1993, comprises companies traded on the Nasdaq National Market® tier of The Nasdaq Stock Market® that are primarily engaged in using biomedical research for the discovery or development of novel treatments or cures for human disease. Companies in the Index must also meet certain other eligibility criteria. On February 7, 2001 the Index was changed to a modified-market-capitalization- weighted Index.

The Nasdaq Stock Market lists nearly 4,500 companies, has a larger dollar volume, and trades more shares per day than any other U.S. market. For more information about Nasdaq, visit the Nasdaq Web Site at www.nasdaq.com or the Nasdaq NewsroomSM at www.nasdaqnews.com.